Enniatin Production by Fusarium Sambucinum: Primary, Secondary, and Unitary Metabolism
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چکیده
منابع مشابه
A highly specific D-hydroxyisovalerate dehydrogenase from the enniatin producer Fusarium sambucinum.
A highly specific D-hydroxyisovalerate (D-HIV) dehydrogenase, which is a key enzyme in depsipeptide synthesis, was purified to near homogeneity from the enniatin-producing fungus Fusarium sambucinum. The enzyme catalyzes the reversible reaction of 2-ketoisovalerate (2-KIV) to D-HIV. It is strictly dependent on NADPH and exhibits a high substrate specificity with respect to 2-KIV. NADH was not a...
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Sixty-two strains of Gibberella pulicaris (anamorph: Fusarium sambucinum) from diseased plants and from soil were tested for tolerance of the furanocoumarin xanthotoxin in vitro. Twenty-one (88%) of the plant-derived strains and two (5%) of the soil-derived strains were highly tolerant ofxanthotoxin. Sixteen selected strains were tested further against 16 furanocoumarins or furanocoumarin precu...
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Twenty-five strains of Fusarium sambucinum grown on wheat kernels were examined for trichothecene production and the synthesis of volatile sesquiterpenes. The volatiles were purged with air and collected on Tenax traps. Adsorbed compounds were eluted from the traps and injected into a gas chromatograph coupled with a mass spectrometer. Ten strains isolated from potato tubers produced high amoun...
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Enniatins are cyclic depsipeptides produced by fungi of the genus Fusarium that are of interest due to their pronounced biological activities; especially enniatins A, A1, B, and B1 possess anticarcinogenic and anti-HIV properties. In the present study, F. tricinctum was grown on seven solid media and in one liquid growth medium with or without addition of peptone or of amino acid precursors in ...
متن کاملEnniatin and Beauvericin Biosynthesis in Fusarium Species: Production Profiles and Structural Determinant Prediction
Members of the fungal genus Fusarium can produce numerous secondary metabolites, including the nonribosomal mycotoxins beauvericin (BEA) and enniatins (ENNs). Both mycotoxins are synthesized by the multifunctional enzyme enniatin synthetase (ESYN1) that contains both peptide synthetase and S-adenosyl-l-methionine-dependent N-methyltransferase activities. Several Fusarium species can produce ENN...
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ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1975
ISSN: 0022-1287
DOI: 10.1099/00221287-86-2-327